Glucosidase 2 subunit beta Recombinant Rabbit Monoclonal Antibody [JE58-41]

• Description:

  Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc2Man9GlcNAc2 oligosaccharide precursor of immature glycoproteins. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia. This protein is involved in the pathway N-glycan metabolism, which is part of Glycan metabolism. View all proteins of this organism that are known to be involved in the pathway N-glycan metabolism and in Glycan metabolism. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants.

• Product Name Alternative:

  80K-H protein antibody AGE-binding receptor 2 antibody AGE-R2 antibody G19P1 antibody GLU2B_HUMAN antibody Glucosidase 2 subunit beta antibody Glucosidase II beta subunit antibody Glucosidase II subunit beta antibody Hepatocystin antibody PCLD antibody PKCSH antibody PLD1 antibody PRKCSH antibody Protein kinase C substrate 60.1 kDa protein heavy chain antibody Protein kinase C substrate 80 Kda protein antibody Protein kinase C substrate 80K-H antibody Protein kinase C substrate, 80 Kda protein antibody

• Abbreviation:

  PRKCSH

• Swiss Prot:

  P14314 Human

• Cellular Locus:

  Endoplasmic reticulum.

• Host:

  Rabbit

• Species Reactivity:

  Human

• Immunogen:

  Synthetic peptide within human Glucosidase 2 subunit beta aa 479-528/528.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IHC-P, IF-Cell, IF-Tissue

• Positive Control:

  Hela cell lysate, A431 cell lysate, MCF-7 cell lysate, human placenta tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000-1:5,000;IHC-P: 1:50-1:200;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 59 kDa.

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3