PI3-kinase p110 subunit beta Recombinant Rabbit Monoclonal Antibody [SC0580]

PI3-kinase p110 subunit beta Recombinant Rabbit Monoclonal Antibody [SC0580]

• Description: Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. p110 expression is restricted to white blood cells. It has been shown to bind p85α and β, but it apparently does not phosphorylate these subunits. p110δ seems to have the capacity to autophosphorylate. p110γ does not interact with the p85 subunits. It has been shown to be activated by α and β γ heterotrimeric G proteins.
• Product Name Alternative: 5-bisphosphate 3-kinase 110 kDa catalytic subunit beta antibody 5-bisphosphate 3-kinase catalytic subunit beta isoform antibody DKFZp779K1237 antibody MGC133043 antibody OTTHUMP00000216901 antibody OTTHUMP00000216904 antibody p110 BETA antibody p110Beta antibody Phosphatidylinositol 3 kinase catalytic beta polypeptide antibody Phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit beta antibody Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit beta isoform antibody Phosphatidylinositol-4 antibody Phosphoinositide 3 kinase catalytic beta polypeptide antibody PI3 kinase p110 subunit beta antibody PI3-kinase subunit beta antibody PI3K antibody PI3K beta antibody PI3K-beta antibody PI3Kbeta antibody PI3KCB antibody PIK3C1 antibody Pik3cb antibody PK3CB_HUMAN antibody PtdIns 3 kinase p110 antibody PtdIns-3-kinase subunit beta antibody PtdIns-3-kinase subunit p110-beta antibody
• Abbreviation: PI3-kinase subunit beta, PI3K-beta, PI3Kbeta, PtdIns-3-kinase subunit beta, PtdIns-3-kinase subunit p110-beta, p110beta, PIK3CB
• CAS Number: 9000-83-3
• Swiss Prot: P42338 Human
• Cellular Locus: Cytoplasm, Nucleus.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within Human PIK3CB aa 5-52 / 1070.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IP, IHC-P, FC
• Positive Control: Jurkat cell lysate, K-562 cell lysate, HeLa cell lysate, MCF7 cell lysate, human liver carcinoma tissue, Hela.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:50-1:100 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 123 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes