Glucosidase 2 subunit beta Recombinant Mouse Monoclonal Antibody [A6H9-R]

• Description:

  Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc (2)Man (9)GlcNAc (2) oligosaccharide precursor of immature glycoproteins. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity). This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants.

• Product Name Alternative:

  80K-H protein antibody AGE-binding receptor 2 antibody AGE-R2 antibody G19P1 antibody GLU2B_HUMAN antibody Glucosidase 2 subunit beta antibody Glucosidase II beta subunit antibody Glucosidase II subunit beta antibody Hepatocystin antibody PCLD antibody PKCSH antibody PLD1 antibody PRKCSH antibody Protein kinase C substrate 60.1 kDa protein heavy chain antibody Protein kinase C substrate 80 Kda protein antibody Protein kinase C substrate 80K-H antibody Protein kinase C substrate, 80 Kda protein antibody

• Abbreviation:

  PRKCSH

• Swiss Prot:

  P14314 Human

• Cellular Locus:

  Endoplasmic reticulum.

• Host:

  Mouse

• Species Reactivity:

  Human

• Immunogen:

  Recombinant protein within human Glucosidase 2 subunit beta aa 51-250.

• Isotype:

  IgG1

• Clone:

  A6H9-R

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Mouse monoclonal Antibody

• Applications:

  WB

• Positive Control:

  HeLa cell lysate, 293T cell lysate, Daudi cell lysate, Jurkat cell lysate, A431 cell lysate.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 59 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3