RBBP5 Rabbit Polyclonal Antibody
CAT:
992-HA500395
Size:
100 µL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RBBP5 Rabbit Polyclonal Antibody
- Description: In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. In association with ASH2L and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.
- Product Name Alternative: RBBP 5 antibody RBBP-5 antibody RBBP5 antibody RBBP5_HUMAN antibody RBQ 3 antibody RBQ3 antibody Retinoblastoma binding protein 5 antibody Retinoblastoma binding protein RBQ3 antibody Retinoblastoma binding protein5 antibody Retinoblastoma-binding protein 5 antibody Retinoblastoma-binding protein RBQ-3 antibody SWD1 antibody SWD1, Set1c WD40 repeat protein, homolog antibody
- Abbreviation: Retinoblastoma-binding protein 5 RBBP-5 Retinoblastoma-binding protein RBQ-3 RBBP5 RBQ3
- CAS Number: 9007-83-4
- Swiss Prot: Q15291 Human, Q8BX09 Mouse,
- Cellular Locus: Nucleus.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthetic peptide within human RBBP5 aa 430-480.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Rabbit polyclonal Antibody
- Applications: WB
- Positive Control: 293 cell lysate, MCF-7 cell lysate, K562 cell lysate, A431 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, L6 cell lysate, N2A cell lysate, RAW264.7 cell lysate.
- Concentration: 2.1 mg/mL
- Dilution: WB: 1:1,000
- Purity: Immunogen affinity purified.
- Form: Liquid
- Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 59 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
- Recombinant Antibody: No