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MVD Rabbit Polyclonal Antibody

CAT: 0992-HA500275Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500275Size:100 µL
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Description
Diphosphomevalonate decarboxylase , most commonly referred to in scientific literature as mevalonate diphosphate decarboxylase.This enzyme converts mevalonate 5-diphosphate (MVAPP) to isopentenyl diphosphate (IPP) through ATP dependent decarboxylation.[1] The two substrates of this enzyme are ATP and mevalonate 5-diphosphate, whereas its 4 products are ADP, phosphate, isopentenyl diphosphate, and CO2.Mevalonate diphosphate decarboxylase catalyzes the final step in the mevalonate pathway. The mevalonate pathway is responsible for the biosynthesis of isoprenoids from acetate.[2] This pathway plays a key role in multiple cellular processes by synthesizing sterol isoprenoids, such as cholesterol, and non-sterol isoprenoids, such as dolichol, heme A, tRNA isopentenyltransferase, and ubiquinone.
CAS Number
9007-83-4
Product Name Alternative
Diphosphomevalonate decarboxylase antibody FP17780 antibody MDDase antibody Mevalonate (diphospho) decarboxylase antibody Mevalonate (diphospho)decarboxylase antibody Mevalonate pyrophosphate decarboxylase antibody MPD antibody Mvd antibody MVD1_HUMAN antibody
Abbreviation
Diphosphomevalonate decarboxylase Mevalonate (diphospho)decarboxylase MDDase Mevalonate pyrophosphate decarboxylase
Swiss Prot
P53602 Human, Q62967 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Synthetic peptide within human MVD aa 350-400 / 400.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
293 cell lysate, A431 cell lysate, rat brain tissue lysate, human liver tissue, human lung tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
43 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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