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CYP7A1 Rabbit Polyclonal Antibody

CAT: 0992-HA500207Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500207Size:100 µL
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Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis.
CAS Number
9007-83-4
Product Name Alternative
Cholesterol 7 alpha hydroxylase antibody Cholesterol 7 alpha monooxygenase antibody Cholesterol 7-alpha-hydroxylase antibody Cholesterol 7-alpha-monooxygenase antibody CP7A antibody CP7A1_HUMAN antibody CYP 7 antibody CYP7 antibody CYP7A1 antibody CYPVII antibody Cytochrome P450 7A1 antibody Cytochrome P450, family 7, subfamily A, polypeptide 1 antibody Cytochrome P450, subfamily VIIA (cholesterol 7 alpha monooxygenase), antibody Cytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase), polypeptide 1 antibody MGC126826 antibody MGC138389 antibody
Abbreviation
Cytochrome P450 7A1, CYP7A1, CYP7
Swiss Prot
P22680 Human, P18125 Rat
Cellular Locus
Endoplasmic reticulum membrane, Microsome membrane.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within human CYP7A1 aa 50-250.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, FC
Positive Control
LO2 cell lysate, Huh7 cell lysate, Hepa1-6 cell lysate, rat liver tissue lysate, SiHa, HeLa.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:200 ;FC: 1:200-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 58 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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