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CYP1B1 Rabbit Polyclonal Antibody

CAT: 0992-HA500494Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500494Size:100 µL
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Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
CAS Number
9007-83-4
Product Name Alternative
Aryl hydrocarbon hydroxylase antibody CP1B antibody CP1B1_HUMAN antibody Cyp1b1 antibody CYPIB1 antibody Cytochrome P450 1B1 antibody Cytochrome P450 family 1 subfamily B polypeptide 1 antibody Cytochrome P450 subfamily I (dioxin inducible) polypeptide 1 (glaucoma 3 primary infantile) antibody Flavoprotein linked monooxygenase antibody GLC3A antibody Microsomal monooxygenase antibody P4501B1 antibody Xenobiotic monooxygenase antibody
Abbreviation
Cytochrome P450 1B1, CYP1B1
Swiss Prot
Q16678 Human, Q64678 Rat
Cellular Locus
Mitochondrion, Endoplasmic reticulum membrane, Microsome membrane.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within human CYP1B1 aa 231-400.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
A549 cell lysate, Hela cell lysate, rat skeletal muscle tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 61 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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