Ly6c Rabbit Polyclonal Antibody

The gene encoding the mouse alloantigen, Ly-6C, maps to chromosome 15 and encodes a 131 amino acid protein that belongs to the Ly-6 family of glycosyl-phosphatidylinositol (GPI)-linked proteins. Ly-6 family members share amino acid homology throughout a distinctive cysteine rich protein domain that incorporates O-linked carbohydrates. Murine Ly-6 molecules have unique patterns of tissue expression during hematopoiesis from multipotential stem cells to lineage committed precursor cells, and on specific leukocyte subpopulations in the peripheral lymphoid tissues. Ly-6C is predominantly expressed on murine peripheral CD8 T cells. Ly-6C is involved in endothelial adhesion, the killing of target cells by CTLs, inducing TCR-mediated activation of IL-2 and IFN-γ production in CD8 T cells and the homing of CD8 T cells. In addition, Ly-6C may act as a signaling molecule of LFA-1 activation.

9007-83-4

Ly 6c antibody Ly6c protein antibody Ly6c1 antibody Ly6c2 antibody Lymphocyte antigen 6 complex antibody Lymphocyte antigen 6 complex locus C antibody Lymphocyte antigen 6C antibody Lymphocyte antigen 6C1 antibody Lymphocyte antigen 6C2 antibody Lymphocyte antigen Ly 6C antibody

Ly6c1, Ly6c2, Ly6c

P0CW02 Mouse, P0CW03 Mouse

Cell membrane.

Synthetic peptide within mouse Ly6c1 aa 75-100.

Non-conjugated

Rabbit polyclonal Antibody

WB, IHC-P

Mouse lung tissue lysate, mouse cerebellum tissue lysate, mouse lung tissue, mouse brain tissue, mouse spleen tissue, mouse heart tissue.

1 mg/mL

WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500

Immunogen affinity purified.

Liquid

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Predicted band size: 14 kDa

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.