Complement factor B Rabbit Polyclonal Antibody

• Description:

  Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

• Product Name Alternative:

  C3/C5 convertase antibody Complement factor B antibody Glycine-rich beta glycoprotein antibody PBF2 antibody Properdin factor B antibody

• Abbreviation:

  Complement factor B : C3/C5 convertase Glycine-rich beta glycoprotein GBG PBF2 Properdin factor B Complement factor B Ba fragment Complement factor B Bb fragment CFB

• Swiss Prot:

  P00751 Human

• Cellular Locus:

  Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat

• Immunogen:

  Recombinant protein within human Complement factor B aa 20-230.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P

• Positive Control:

  Rat liver tissue lysates, SKOV-3, human liver tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:100-1:500

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 86 kDa.

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4