Aldolase B Rabbit Polyclonal Antibody

Aldolase B also known as fructose-bisphosphate aldolase B or liver-type aldolase is one of three isoenzymes (A, B, and C) of the class I fructose 1,6-bisphosphate aldolase enzyme (EC 4.1.2.13), and plays a key role in both glycolysis and gluconeogenesis. The generic fructose 1,6-bisphosphate aldolase enzyme catalyzes the reversible cleavage of fructose 1,6-bisphosphate (FBP) into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate (DHAP) as well as the reversible cleavage of fructose 1-phosphate (F1P) into glyceraldehyde and dihydroxyacetone phosphate. In mammals, aldolase B is preferentially expressed in the liver, while aldolase A is expressed in muscle and erythrocytes and aldolase C is expressed in the brain. Slight differences in isozyme structure result in different activities for the two substrate molecules: FBP and fructose 1-phosphate. Aldolase B exhibits no preference and thus catalyzes both reactions, while aldolases A and C prefer FBP. In humans, aldolase B is encoded by the ALDOB gene located on chromosome 9. The gene is 14,500 base pairs long and contains 9 exons. Defects in this gene have been identified as the cause of hereditary fructose intolerance (HFI).

9007-83-4

ALDB antibody ALDO B antibody ALDO2 antibody ALDOB antibody ALDOB_HUMAN antibody Aldolase 2 antibody Aldolase B antibody Aldolase B fructose bisphosphate antibody Aldolase2 antibody AldolaseB antibody EC 4.1.2.13 antibody Fructose bisphosphate aldolase B antibody Fructose-bisphosphate aldolase B antibody Liver type aldolase antibody Liver-type aldolase antibody MS1077 antibody

ALDOB

P05062 Human, Q91Y97 Mouse, P00884 Rat

Cytoplasm, Cytoskeleton.

Recombinant protein within Human Aldolase B aa 1-189 / 364.

Non-conjugated

Rabbit polyclonal Antibody

WB, IHC-P, FC

SH-SY5Y cell lysate, human liver tissue lysate, mouse liver tissue lysate, mouse kidney tissue lysate, rat kidney tissue, human liver tissue, human kidney tissue, mouse small intestine tissue, SH-SY5Y.

1 mg/mL

WB:1:500-1:2,000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100

Immunogen affinity purified.

Liquid

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Predicted band size: 39 kDa

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.