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p50 dynamitin Rabbit Polyclonal Antibody

CAT: 0992-HA500029Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500029Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 23 subunits (11 individual proteins ranging in size from 22 to 150 kD). The subunit is commonly referred to as p50 or dynamitin. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that bind to two copies of p150-glued (DCTN1) and two copies of p24 (DCTN3) to form the dynactin shoulder domain.
CAS Number
9007-83-4
Product Name Alternative
50 kD dynein associated polypeptide antibody 50 kDa dynein associated polypeptide antibody 50 kDa dynein-associated polypeptide antibody DCTN-50 antibody DCTN2 antibody DCTN2_HUMAN antibody DCTN50 antibody dynactin 2 (p50) antibody dynactin 2 antibody dynactin complex 50 kD subunit antibody Dynactin complex 50 kDa subunit antibody Dynactin subunit 2 antibody DYNAMITIN antibody p50 dynamitin antibody RBP50 antibody
Abbreviation
Dynactin subunit 2 50 kDa dynein-associated polypeptide Dynactin complex 50 kDa subunit DCTN-50 p50 dynamitin
Swiss Prot
Q13561 Human, Q99KJ8 Mouse, Q6AYH5 Rat
Cellular Locus
Cytoplasm, Cytoskeleton, Dynein, Membrane, Microtubule.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human p50 dynamitin aa 1-200.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
SHSY5Y cell lysate, mouse brain tissue lysate, PANC-1, rat cerebellum tissue, SHSY5Y.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:50-1:100;IHC-P: 1:200-1:1,000;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 44 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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