p50 dynamitin Rabbit Polyclonal Antibody

p50 dynamitin Rabbit Polyclonal Antibody

• Description: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 23 subunits (11 individual proteins ranging in size from 22 to 150 kD). The subunit is commonly referred to as p50 or dynamitin. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that bind to two copies of p150-glued (DCTN1) and two copies of p24 (DCTN3) to form the dynactin shoulder domain.
• Product Name Alternative: 50 kD dynein associated polypeptide antibody 50 kDa dynein associated polypeptide antibody 50 kDa dynein-associated polypeptide antibody DCTN-50 antibody DCTN2 antibody DCTN2_HUMAN antibody DCTN50 antibody dynactin 2 (p50) antibody dynactin 2 antibody dynactin complex 50 kD subunit antibody Dynactin complex 50 kDa subunit antibody Dynactin subunit 2 antibody DYNAMITIN antibody p50 dynamitin antibody RBP50 antibody
• Abbreviation: Dynactin subunit 2 50 kDa dynein-associated polypeptide Dynactin complex 50 kDa subunit DCTN-50 p50 dynamitin
• CAS Number: 9007-83-4
• Swiss Prot: Q13561 Human, Q99KJ8 Mouse, Q6AYH5 Rat
• Cellular Locus: Cytoplasm, Cytoskeleton, Dynein, Membrane, Microtubule.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within human p50 dynamitin aa 1-200.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC
• Positive Control: SHSY5Y cell lysate, mouse brain tissue lysate, PANC-1, rat cerebellum tissue, SHSY5Y.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000;IF-Cell: 1:50-1:100;IHC-P: 1:200-1:1,000;FC: 1:50-1:100
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 44 kDa.
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No