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Dynamin 1 Rabbit Polyclonal Antibody

CAT: 0992-ER1802-77Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1802-77Size:100 µL
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Description
Members of the Dynamin family, including Dynamin I and Dynamin II, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression found in testis. Both dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the dynamins and effectors of their GTPase activity). The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to clathrin coated pits by SH3 domain interaction with amphiphysin, a protein highly expressed in brain.
CAS Number
9007-83-4
Product Name Alternative
B dynamin antibody D100 antibody DNM 1 antibody DNM antibody DNM1 antibody DYN1_HUMAN antibody Dynamin antibody Dynamin-1 antibody Dynamin1 antibody
Abbreviation
DNM1, DNM
Swiss Prot
Q05193 Human, P39053 Mouse, P21575 Rat
Cellular Locus
Cytoplasm, Cytoskeleton, Microtubule.
Host
Rabbit
Species Reactivity
Mouse, Rat, Human
Immunogen
Recombinant protein within human Dynamin 1 aa 565-770.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Mouse brain tissue lysate, Mouse brain tissue, rat brain tissue, mouse cerebellum tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 97 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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