Dynamin 1 Rabbit Polyclonal Antibody

Dynamin 1 Rabbit Polyclonal Antibody

• Description: Members of the Dynamin family, including Dynamin I and Dynamin II, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression found in testis. Both dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the dynamins and effectors of their GTPase activity). The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to clathrin coated pits by SH3 domain interaction with amphiphysin, a protein highly expressed in brain.
• Product Name Alternative: B dynamin antibody D100 antibody DNM 1 antibody DNM antibody DNM1 antibody DYN1_HUMAN antibody Dynamin antibody Dynamin-1 antibody Dynamin1 antibody
• Abbreviation: DNM1, DNM
• CAS Number: 9007-83-4
• Swiss Prot: Q05193 Human, P39053 Mouse, P21575 Rat
• Cellular Locus: Cytoplasm, Cytoskeleton, Microtubule.
• Host: Rabbit
• Species Reactivity: Mouse, Rat, Human
• Immunogen: Recombinant protein within human Dynamin 1 aa 565-770.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P
• Positive Control: Mouse brain tissue lysate, Mouse brain tissue, rat brain tissue, mouse cerebellum tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 97 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No