NF-kappaB p105/p50 Rabbit Polyclonal Antibody

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MBS8534914-05	NF-kappaB (p105/p50)
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MBS8542159-03	NF-kappaB (p105/p50) Rabbit pAb
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MBS8542159-01	NF-kappaB (p105/p50) Rabbit pAb

CAT:

992-R1309-9

Size:

100 µL

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NF-kappaB p105/p50 Rabbit Polyclonal Antibody

Description: NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators.
Alternative Name: DKFZp686C01211 antibody DNA binding factor KBF1 antibody DNA binding factor KBF1 EBP1 antibody DNA-binding factor KBF1 antibody EBP 1 antibody EBP-1 antibody EBP1 antibody KBF1 antibody MGC54151 antibody NF kappa B antibody NF kappaB antibody NF kappabeta antibody NF kB1 antibody NFkappaB antibody NFKB 1 antibody NFKB p105 antibody NFKB p50 antibody Nfkb1 antibody NFKB1_HUMAN antibody Nuclear factor kappa B DNA binding subunit antibody Nuclear factor kappa-B, subunit 1 antibody Nuclear factor NF kappa B p105 subunit antibody Nuclear factor NF kappa B p50 subunit antibody Nuclear factor NF-kappa-B p50 subunit antibody Nuclear factor of kappa light chain gene enhancer in B cells 1 antibody Nuclear factor of kappa light polypeptide gene enhancer in B cells 1 antibody Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody p105 antibody p50 antibody p84/NF-kappa-B1 p98 antibody Transcription factor NFKB2 antibody NF-κB p105/p50 NF κB p105/p50 NF-κB p105/p50
Abbreviation: NFKB1
Swiss Prot: P19838 Human
Cellular Locus: Nucleus. Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within human NFkB p105 aa 320-366.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: Raji, Hela, HepG2, human breast carcinoma tissue
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000;IF-Cell: 1:200-1:500;IHC-P: 1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: ~50/105kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Complementary Product Range

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