Insulin Recombinant Rabbit Monoclonal Antibody [SA0410]

• Description:

  Insulin (from Latin insula, 'island') is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of glucose from the blood into liver, fat and skeletal muscle cells. In these tissues the absorbed glucose is converted into either glycogen via glycogenesis or fats (triglycerides) via lipogenesis, or, in the case of the liver, into both. Glucose production and secretion by the liver is strongly inhibited by high concentrations of insulin in the blood. Circulating insulin also affects the synthesis of proteins in a wide variety of tissues. It is therefore an anabolic hormone, promoting the conversion of small molecules in the blood into large molecules inside the cells. Low insulin levels in the blood have the opposite effect by promoting widespread catabolism, especially of reserve body fat.

• Product Name Alternative:

  IDDM antibody IDDM1 antibody IDDM2 antibody ILPR antibody ins antibody INS_HUMAN antibody Insulin A chain antibody Insulin B chain antibody IRDN antibody MODY10 antibody Preproinsulin antibody Proinsulin antibody Proinsulin precursor antibody

• Abbreviation:

  INS Insulin Insulin B chain Insulin A chain

• Swiss Prot:

  P01308 Human, P01325 Mouse, P01322 Rat

• Cellular Locus:

  Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within human Insulin aa 15-110.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  IF-Cell, IF-Tissue, IHC-P, mIHC, IHC-Fr

• Positive Control:

  Mouse pancreas tissue, rat pancreas tissue, human pancreas tissue.

• Concentration:

  1 mg/mL

• Dilution:

  IF-Cell: 1:200-1:500 ;IF-Tissue: 1:200-1:500 ;IHC-P: 1:20,000 ;mIHC: 1:8,000 ;IHC-Fr: 1:1,000

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 12 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3