MMP-13 Recombinant Rabbit Monoclonal Antibody [JF0893]

MMP-13 Recombinant Rabbit Monoclonal Antibody [JF0893]

• Description: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen types I, II and III. MMP-13 has wide substrate specificity, and its physiologic expression is limited to situations in which rapid and effective remodeling of collagenous ECM takes place, such as fetal bone development and adult bone remodeling.
• Product Name Alternative: CLG 3 antibody CLG3 antibody Collagenase 3 antibody Collagenase3 antibody MANDP1 antibody Matrix metallopeptidase 13 (collagenase 3) antibody Matrix Metalloproteinase 13 antibody Matrix metalloproteinase-13 antibody MMP 13 antibody MMP-13 antibody Mmp13 antibody MMP13_HUMAN antibody
• Abbreviation: MMP-13, MMP13
• CAS Number: 9000-83-3
• Swiss Prot: P45452 Human
• Cellular Locus: Extracellular matrix, Secreted.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within human MMP13 aa 390-430.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
• Positive Control: HeLa cell lysate, HEK-293 cell lysate, Jurkat cell lysate, MDA-MB-231 cell lysate, SW480 cell lysate, HeLa, human breast tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IF-Cell: 1:100 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 54 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes