MMP-12 Recombinant Rabbit Monoclonal Antibody [SR03-23]
CAT:
992-ET1602-42
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
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MMP-12 Recombinant Rabbit Monoclonal Antibody [SR03-23]
- Description: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 (also designated macrophage metalloelastase) is produced in alveolar macrophages and degrades elastin. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration through the epidermal and vascular basement membranes in inflammatory disorders.
- Product Name Alternative: EC 3.4.24.65 antibody HME antibody Macrophage elastase antibody Macrophage metalloelastase antibody Macrophage metaloelastase antibody Matrix metallopeptidase 12 (macrophage elastase) antibody Matrix metalloprotease 12 antibody Matrix metalloproteinase-12 antibody ME antibody MGC138506 antibody MME antibody MMP 12 antibody MMP-12 antibody Mmp12 antibody MMP12_HUMAN antibody
- Abbreviation: MME, ME, hME, MMP-12
- CAS Number: 9000-83-3
- Swiss Prot: P39900 Human, P34960 Mouse, Q63341 Rat
- Cellular Locus: Secreted.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthetic peptide within Human MMP12 aa 421-470 / 470.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Recombinant Rabbit monoclonal Antibody
- Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
- Positive Control: A549 cell lysate, Hela cell lysate, MCF-7 cell lysate, THP-1 cell lysate, human breast carcinoma tissue lysate, mouse lung tissue lysate, rat lung tissue lysate.
- Concentration: 1 mg/mL
- Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:20-1:50 ;IF-Tissue: 1:20-1:50 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
- Purity: Protein A affinity purified.
- Form: Liquid
- Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 54 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Recombinant Antibody: Yes