Fatty Acid Synthase Recombinant Rabbit Monoclonal Antibody [JJ0939]

Fatty Acid Synthase Recombinant Rabbit Monoclonal Antibody [JJ0939]

• Description: Fatty acid biosynthesis is mediated by seven catalytic enzymes and an acyl carrier protein (ACP), to which various acyl intermediates are covalently attached. Fatty Acid Synthase (FAS) is the anabolic enzyme that contains the seven unique catalytic sites and mediates the conversion of acetyl-CoA and malonyl-CoA, in the presence of the cofactor NADPH, into long-chain saturated fatty acids, such as palmitate. Human Fatty Acid Synthase cDNA encodes a 2,504 amino acid protein. Catalytically active Fatty Acid Synthase is a homodimer. Human Fatty Acid Synthase mRNA is variably expressed with abundant levels present in brain, lung and liver. Fatty acid synthetic metabolism is abnormally elevated in tumor cells and may support cell growth or survival of malignant cancers.
• Product Name Alternative: [Acyl-carrier-protein] S acetyltransferase antibody [Acyl-carrier-protein] S malonyltransferase antibody 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase antibody 3-oxoacyl-[acyl-carrier-protein] reductase antibody 3-oxoacyl-[acyl-carrier-protein] synthase antibody Enoyl-[acyl-carrier-protein] reductase antibody FAS antibody FAS_HUMAN antibody FASN antibody Fatty acid synthase antibody MGC14367 antibody MGC15706 antibody OA 519 antibody Oleoyl-[acyl-carrier-protein] hydrolase antibody SDR27X1 antibody Short chain dehydrogenase/reductase family 27X member 1 antibody
• Abbreviation: FASN
• CAS Number: 9000-83-3
• Swiss Prot: P49327 Human, P19096 Mouse, P12785 Rat
• Cellular Locus: Cytoplasm, Melanosome.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within C-terminal human Fatty Acid Synthase.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
• Positive Control: HeLa, HeLa cell lysate, HEK-293 cell lysate, A549 cell lysate, C2C12 cell lysate, L-929 cell lysate, SK-Br-3, A549, RH-35, MCF-7, SW480, human breast carcinoma tissue, mouse colon tissue, human liver tissue, HeLa.
• Concentration: 1 mg/mL
• Dilution: WB: 1:5,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:50-1:200 ;FC: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 273 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes