Spermine synthase Recombinant Rabbit Monoclonal Antibody [JE61-85]

Spermine synthase Recombinant Rabbit Monoclonal Antibody [JE61-85]

• Description: This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS). Multiple transcript variants encoding different isoforms have been found for this gene. Spermine synthase is an enzyme that converts spermidine into spermine. This enzyme catalyses the following chemical reaction. Spermine synthase is a form of polyamine that is in all eukaryotes and plays a role in a variety of biological functions in plants. Its structure consists of two identical monomers of 41 kDa with three domains each, creating a homodimer formed via dimerization. The interactions between one of the three domains, the N-terminals of the monomers, is responsible for dimerization as that is where the active site is located; the central terminal consisting of four β- strands structurally forming a lid for the third domain, the C-terminal domain.
• Product Name Alternative: MRSR antibody SMS antibody Snyder Robinson X linked mental retardation syndrome antibody Spermidine aminopropyltransferase antibody Spermine synthase antibody SPMSY antibody SpS antibody SPSY_HUMAN antibody SRS antibody
• Abbreviation: SMS
• CAS Number: 9000-83-3
• Swiss Prot: P52788 Human, P97355 Mouse,
• Cellular Locus: Cytosol, extracellular exosome.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human Spermine synthase aa 100-150/366.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: Hela cell lysate, Jurkat cell lysate, K562 cell lysate, rat uterus tissue lysate, mouse testis tissue lysate, human placenta tissue, human prostate tissue, Hela.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50;IHC-P: 1:50-1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 41 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes