Phospho-Glycogen synthase 1 (S641) Recombinant Rabbit Monoclonal Antibody [SR46-06]

Phospho-Glycogen synthase 1 (S641) Recombinant Rabbit Monoclonal Antibody [SR46-06]

• Description: Glycogen [starch] synthase belongs to the mammalian/fungal glycogen synthase family of proteins. Two forms of this protein exist, a liver form and a muscle form, both of which have the same function in the glycogen biosynthesis pathway. Glycogen synthase transfers the glycosyl residue from UDP-Glucose to the nonreducing end of ?-1,4-glucan. The liver glycogen synthase protein is truncated by 34 amino acids compared to the muscle form. However, these enzymes differ significantly in their amino- and carboxyl-terminal regions. Muscle glycogen synthase serves to fuel muscular activity only and is regulated by muscle contraction and by catecholamines. Liver glycogen synthase mediates blood glucose homeostasis in response to nutritional cues. Defects in the gene encoding liver glycogen synthase results in glycogen storage disease type 0 (GSD0), a rare form of fasting ketotic hypoglycemia.
• Product Name Alternative: Glycogen [starch] synthase antibody Glycogen synthase 1 (muscle) antibody Glycogen synthase 1 antibody GSY antibody GYS antibody Gys1 antibody GYS1_HUMAN antibody muscle antibody
• Abbreviation: GYS1
• CAS Number: 9000-83-3
• Swiss Prot: P13807 Human, Q9Z1E4 Mouse,
• Cellular Locus: Cytoplasm
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser641 of Human Glycogen synthase 1.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P, IP
• Positive Control: SK-Br-3 cell lysate, A431 cell lysate, HepG2 cell lysate, Mouse liver tissue lysate, A549, NIH/3T3, mouse liver tissue, mouse skeletal muscle tissue, mouse smooth muscle tissue, rat skeletal muscle tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500 ;IF-Cell: 1:50 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 84 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes