SHP2 Recombinant Rabbit Monoclonal Antibody [SN72-02]

SHP2 Recombinant Rabbit Monoclonal Antibody [SN72-02]

• Description: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus .Positively regulates MAPK signal transduction pathway.Dephosphorylates GAB1, ARHGAP35 and EGFR.Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulation of its RhoA binding activity.Dephosphorylates CDC73.Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification.
• Product Name Alternative: BPTP3 antibody CFC antibody JMML antibody METCDS antibody MGC14433 antibody NS1 antibody OTTHUMP00000166107 antibody OTTHUMP00000166108 antibody Protein tyrosine phosphatase 2 antibody Protein tyrosine phosphatase 2C antibody Protein tyrosine phosphatase non receptor type 11 antibody Protein-tyrosine phosphatase 1D antibody Protein-tyrosine phosphatase 2C antibody PTN11_HUMAN antibody PTP-1D antibody PTP-2C antibody PTP1D antibody PTP2C antibody PTPN11 antibody SAP2 antibody SH-PTP2 antibody SH-PTP3 antibody SH2 domain containing protein tyrosine phosphatase 2 antibody SHP 2 antibody SHP-2 antibody Shp2 antibody SHPTP2 antibody SHPTP3 antibody Syp antibody Tyrosine-protein phosphatase non-receptor type 11 antibody
• Abbreviation: PTP-1D, PTP-2C, SHP-2, Shp2, PTPN11
• CAS Number: 9000-83-3
• Swiss Prot: Q06124 Human, P35235 Mouse, P41499 Rat
• Cellular Locus: Cytoplasm, Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within N-terminal human SHP2.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IP, IHC-P
• Positive Control: K-562 cell lysate, 293T cell lysate, NIH/3T3 cell lysate, mouse brain tissue lysate, mouse heart tissue lysate, rat brain tissue lysate, rat heart tissue lysate, human tonsil tissue, mouse testis tissue, rat testis tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:5,000 ;IP: Use at an assay dependent concentration. ;IHC-P: 1:500
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 68 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes