YB1 Recombinant Rabbit Monoclonal Antibody [ST0432]

YB1 Recombinant Rabbit Monoclonal Antibody [ST0432]

• Description: Y-box binding protein YB-1 (also known as CCAAT-binding transcription factor, enhancer factor I subunit A and DNA-binding protein B) belongs to a family of multifunctional proteins which regulate both transcription and translation. Y-box proteins interact with a wide variety of nucleic acid structures to act as transcription factors and mRNA masking proteins. The modular structure of Y-box proteins includes a highly conserved N-terminal cold-shock domain (CSD, equivalent to the bacterial cold-shock proteins) and four basic C-terminal domains containing Arginine clusters and aromatic residues. YB-1 plays a role in cell proliferation as an activator of growth-associated gene expression. YB-1 is also a repressor of the cell death-associated gene FAS. YB-1 may play an important role in controlling cell survival by regulating the expression of cell growth-associated and death-associated genes.
• Product Name Alternative: BP 8 antibody CBF-A antibody CCAAT binding transcription factor I subunit A antibody CCAAT-binding transcription factor I subunit A antibody CSDA2 antibody CSDB antibody DBPB antibody DNA binding protein B antibody DNA-binding protein B antibody EFI-A antibody Enhancer factor I subunit A antibody MDR NF1 antibody MGC104858 antibody MGC110976 antibody MGC117250 antibody NSEP 1 antibody NSEP1 antibody Nuclease sensitive element binding protein 1 antibody Nuclease-sensitive element-binding protein 1 antibody p50 antibody Q15905 antibody Y-box binding protein 1 antibody Y-box transcription factor antibody Y-box-binding protein 1 antibody YB 1 antibody YB-1 antibody YBOX1_HUMAN antibody YBX 1 antibody ybx1 antibody
• Abbreviation: CBF-A, DBPB, EFI-A, YB-1, YBX1
• CAS Number: 9000-83-3
• Swiss Prot: P67809 Human, P62960 Mouse, P62961 Rat
• Cellular Locus: Cytoplasm, Nucleus, Cytoplasmic granule, Secreted.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human YB1 aa 275-324 / 324.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
• Positive Control: HeLa cell lysate, Jurkat cell lysate, PC-12, human kidney tissue, mouse colon tissue, mouse stomach tissue, human prostate carcinoma tissue, Hela.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:5,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 36 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes