Moesin Recombinant Rabbit Monoclonal Antibody [SC69-01]

Moesin Recombinant Rabbit Monoclonal Antibody [SC69-01]

• Description: Ezrin, Moesin and Radixin belong to a family of highly homologous Actin-associated proteins that are localized just beneath the plasma membrane. These proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share more than 70% homology with Ezrin and are co-expressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation.
• Product Name Alternative: Epididymis luminal protein 70 antibody HEL70 antibody Membrane organizing extension spike protein antibody Membrane-organizing extension spike protein antibody MOES_HUMAN antibody Moesin antibody Moesin/anaplastic lymphoma kinase fusion protein antibody Msn antibody MSN/ALK fusion antibody
• Abbreviation: MSN
• CAS Number: 9000-83-3
• Swiss Prot: P26038 Human, P26041 Mouse, O35763 Rat
• Cellular Locus: Cell membrane, Apical cell membrane, microvillus membrane, cytoskeleton, microvillus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Moesin aa 455-500 / 577.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP
• Positive Control: C6 cell lysate, Mouse heart tissue lysate, Rat heart tissue lysate, Raji cell lysate, SH-SY5Y cell lysate, HeLa, C6, human lung tissue, human spleen tissue, mouse lung tissue, mouse spleen tissue, rat lung tissue, rat spleen tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000 ;IF-Cell: 1:100 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:200-1:1,000 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 68 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes