PI 3 Kinase Class 3 Recombinant Rabbit Monoclonal Antibody [SY0286]

PI 3 Kinase Class 3 Recombinant Rabbit Monoclonal Antibody [SY0286]

• Description: Phosphatidylinositol 3-kinase catalytic subunit type 3 is an enzyme subunit that in humans is encoded by the PIK3C3 gene. It's a class III phosphoinositide 3-kinase. It is ubiquitously expressed with predominant expression in skeletal muscle and is believed to participate in endosome to lysosome transport, multivesicular body formation, autophagy and retrograde endosome to Golgi transport. PI 3-kinase p100 is the catalytic subunit of class III PI3Ks and forms a heterodimer with p150, a regulatory subunit of class 3 PI3Ks. PI 3-kinase p100 exclusively phosphorylates phosphatidylinositol to produce PtdIns3P. Unlike class I PI3Ks, whose activities are enhanced in the presence of magnesium, PI 3-kinase p100 activity is enhanced by manganese. Its activity can also be regulated by nutrients, suggesting an important role of PI-3 kinase p100 in the regulation of mTOR protein synthesis and autophagy.
• Product Name Alternative: hVps34 antibody MGC61518 antibody Phosphatidylinositol 3 kinase catalytic subunit type 3 antibody Phosphatidylinositol 3 kinase class 3 antibody Phosphatidylinositol 3 kinase p100 subunit antibody Phosphatidylinositol 3-kinase catalytic subunit type 3 antibody Phosphatidylinositol 3-kinase p100 subunit antibody Phosphoinositide 3 kinase class 3 antibody Phosphoinositide-3-kinase class 3 antibody PI3 kinase type 3 antibody PI3-kinase type 3 antibody PI3K type 3 antibody Pik3c3 antibody PK3C3_HUMAN antibody PtdIns 3 kinase type 3 antibody PtdIns-3-kinase type 3 antibody Vps 34 antibody Vps34 antibody
• Abbreviation: PI3-kinase type 3, PI3K type 3, PtdIns-3-kinase type 3, PIK3C3
• CAS Number: 9000-83-3
• Swiss Prot: Q8NEB9 Human, Q6PF93 Mouse, O88763 Rat
• Cellular Locus: Midbody, Late endosome, Cytoplasmic vesicle.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human PI 3 Kinase Class 3 aa 830-870.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: IHC-P, FC
• Positive Control: Human stomach cancer tissue, mouse brain tissue, rat brain tissue, A549.
• Concentration: 1 mg/mL
• Dilution: IHC-P: 1:50-1:200 ;FC: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 102 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes