Smad1 Recombinant Rabbit Monoclonal Antibody [SY0254]

Smad1 Recombinant Rabbit Monoclonal Antibody [SY0254]

• Description: Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.
• Product Name Alternative: BSP-1 antibody BSP1 antibody HsMAD1 antibody JV4-1 antibody JV41 antibody MAD homolog 1 antibody MAD mothers against decapentaplegic homolog 1 antibody Mad related protein 1 antibody Mad-related protein 1 antibody MADH1 antibody MADR1 antibody Mothers against decapentaplegic homolog 1 antibody Mothers against DPP homolog 1 antibody SMA- AND MAD-RELATED PROTEIN 1 antibody SMAD 1 antibody SMAD family member 1 antibody SMAD mothers against DPP homolog 1 antibody Smad1 antibody SMAD1_HUMAN antibody TGF beta signaling protein 1 antibody Transforming growth factor-beta-signaling protein 1 antibody
• Abbreviation: MAD homolog 1, Mothers against DPP homolog 1, SMAD 1, Smad1, hSMAD1, BSP-1, SMAD1
• CAS Number: 9000-83-3
• Swiss Prot: Q15797 Human, P70340 Mouse
• Cellular Locus: Cytoplasm, Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthetic peptide within human Smad1 aa 150-200.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P
• Positive Control: Hela, PANC-1, MCF-7, A431, mouse stomach tissue, p19.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;IHC-P: 1:50-1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 52 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes