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GABRA4 Rabbit Polyclonal Antibody

CAT: 0992-ER1901-60Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1901-60Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gamma-aminobutyric acid receptor subunit alpha-4 is a protein that in humans is encoded by the GABRA4 gene. Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.
CAS Number
9007-83-4
Product Name Alternative
GABA (A) receptor subunit alpha 4 antibody GABA (A) receptor subunit alpha-4 antibody GABR A4 antibody GABRA 4 antibody Gabra4 antibody Gamma aminobutyric acid (GABA) A receptor alpha 4 antibody Gamma aminobutyric acid A receptor alpha 4 antibody Gamma aminobutyric acid receptor alpha 4 subunit antibody Gamma aminobutyric acid receptor subunit alpha 4 antibody Gamma-aminobutyric acid receptor subunit alpha-4 antibody GBRA4_HUMAN antibody
Abbreviation
GABRA4
Swiss Prot
P48169 Human, Q9D6F4 Mouse, P28471 Rat
Cellular Locus
Postsynaptic cell membrane, cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within mouse GABRA4 aa 19-68 / 552.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
SH-SY5Y cell lysates, rat brain tissue, mouse brain tissue, SH-SY5Y.
Concentration
1 mg/mL
Dilution
WB:1:500-1:2,000 ;IHC-P:1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size 61 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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