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GABRD Rabbit Polyclonal Antibody

CAT: 0992-ER1901-54Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1901-54Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rα1-6, GABAA R β1-3, GABAA Rγ1-3, GABAA Rδ, GABAA Rε, GABAA Rρ1 and GABAA Rρ2. The GABAB family is composed of GABAB R1α and GABAB R1β. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.
CAS Number
9007-83-4
Product Name Alternative
GABA (A) receptor subunit delta antibody Gabrd antibody Gamma aminobutyric acid GABA A receptor delta antibody Gamma aminobutyric acid receptor delta subunit precursor GABA A receptor antibody Gamma-aminobutyric acid receptor subunit delta antibody GBRD_HUMAN antibody MGC45284 antibody
Abbreviation
Gabrd
Swiss Prot
O14764 Human, P18506 Mouse
Cellular Locus
Postsynaptic cell membrane, cell membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within rat GABRD aa 1-80/449.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, FC
Positive Control
HT-29 cell lysates, MCF-7.
Concentration
1 mg/mL
Dilution
WB:1:1,000-1:3,000 ;FC:1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 51 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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