alpha Actinin Rabbit Polyclonal Antibody

alpha Actinin Rabbit Polyclonal Antibody

• Description: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
• Product Name Alternative: actinin 1 smooth muscle antibody Actinin alpha 1 antibody actinin, alpha 1 antibody ACTN 1 antibody Actn1 antibody ACTN1_HUMAN antibody Alpha Actinin 1 antibody Alpha actinin cytoskeletal isoform antibody Alpha-actinin cytoskeletal isoform antibody Alpha-actinin-1 antibody BDPLT15 antibody F actin cross linking protein antibody F-actin cross-linking protein antibody FLJ40884 antibody FLJ54432 antibody Non muscle alpha actinin 1 antibody Non-muscle alpha-actinin-1 antibody
• Abbreviation: ACTN1
• CAS Number: 9007-83-4
• Swiss Prot: P12814 Human, Q7TPR4 Mouse, Q9Z1P2 Rat
• Cellular Locus: Cell junction, Cell membrane, Cell projection, Cytoplasm, Plasma membrane. Cytoskeleton.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within Human alpha Actinin aa 388-619 / 892.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC
• Positive Control: A431 cell lysate, Rat colon tissue lysate, mouse colon tissue lysates, SH-SY5Y, SiHa, MG-63, human colon cancer tissue, human kidney tissue, mouse colon tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50 -1:200;FC: 1:50-1:100
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 103 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No