MSH6 Mouse Monoclonal Antibody [A4C4]

MSH6 Mouse Monoclonal Antibody [A4C4]

• Description: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
• Product Name Alternative: DNA mismatch repair protein Msh6 antibody G/T mismatch binding protein antibody G/T mismatch-binding protein antibody GTBP antibody GTMBP antibody hMSH6 antibody HNPCC 5 antibody HNPCC5 antibody HSAP antibody MSH 6 antibody MSH6 antibody MSH6_HUMAN antibody mutS (E. coli) homolog 6 antibody MutS alpha 160 kDa subunit antibody MutS homolog 6 (E. coli) antibody mutS homolog 6 antibody MutS-alpha 160 kDa subunit antibody p160 antibody Sperm associated protein antibody
• Abbreviation: DNA mismatch repair protein Msh6 hMSH6 G/T mismatch-binding protein MutS protein homolog 6 MutS-alpha 160 kDa subunit (p160 MSH6 GTBP
• CAS Number: 9007-83-4
• Swiss Prot: P52701 Human, P54276 Mouse
• Cellular Locus: Nucleus, Chromosome.
• Host: Mouse
• Species Reactivity: Human, Mouse
• Immunogen: Synthetic peptide corresponding to C-terminal Human MSH6.
• Isotype: IgG2b
• Conjugation: Non-conjugated
• Type: Mouse monoclonal Antibody
• Applications: WB, IHC-P, IF-Tissue, IF-Cell, IP
• Positive Control: SH-SY5Y cell lysate, 293T cell lysate, NIH/3T3 cell lysate, A549, RAW264.7, human breast carcinoma tissue, mouse testis tissue, human thyroid tissue, human colon carcinoma tissue, human skin tissue, human esophagus tissue, human placenta tissue, mouse colon tissue, mouse placenta tissue, human gastric carcinoma tissue, mouse spleen tissue, mouse small intestine tissue.
• Concentration: 2 mg/mL
• Dilution: WB: 1:500-1:2,000 ;IF-Tissue: 1:50 ;IHC-P: 1:200-1:1,000 ;IF-Cell: 1:100 ;IP: 1-2μg/sample
• Purity: Protein G affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 153 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No