SCA-1 Rabbit Polyclonal Antibody

Sca-1 stands for "Stem cells antigen-1" (official gene symbol: Ly6a). It consist of 18-kDa mouse glycosyl phosphatidylinositol-anchored cell surface protein (GPI-AP) of the LY6 gene family. It is the common biological marker used to identify hematopoitic stem cell (HSC) along with other markers. Sca-1 has a regenerative role in cardiac repair: Host cells with specific Sca-1+CD31− markers arise upon myocardial infarction, with evidence of expression of Sca-1 protein. Sca-1 plays a role in hematopoietic progenitor/stem cell lineage fate and c-kit expression. Sca-1+ HSCs can be found in the adult bone marrow, fetal liver and mobilized peripheral blood and spleen within the adult animal. An anti-Sca-1 Ab is frequently used in combination with negative selection for expression of a number of cell surface markers characteristic of differentiated cells of hematolymphoid lineages (Lin-) to identify and isolate murine HSCs.

9007-83-4

Ly-6A.2/Ly-6E. antibody Ly-6A.2/Ly-6E.1 antibody Ly6a antibody LY6A_MOUSE antibody Ly6al antibody Lymphocyte antigen 6A-2/6E-1 antibody Lymphocyte antigen Ly 6A.2/Ly 6E.1 antibody SCA-1 antibody Stem cell antigen 1 antibody T cell activating protein antibody T-cell-activating protein antibody TAP antibody

SCA-1,Ly-6A.2/Ly-6E.1,TAP

P05533 Mouse

Cell membrane

Synthetic peptide within Mouse SCA-1 aa 51-94.

Non-conjugated

Rabbit polyclonal Antibody

WB, IF-Cell

Mouse kidney tissue lysate, NIH/3T3 cell lysate.

1 mg/mL

WB: 1:1,000

Immunogen affinity purified.

Liquid

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Predicted band size: 14 kDa

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.