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NHE-1 Rabbit Polyclonal Antibody

CAT: 0992-ER1902-51Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1902-51Size:100 µL
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Description
The sodium-hydrogen antiporter 1 (NHE-1) also known as sodium/hydrogen exchanger 1 or SLC9A1 (SoLute Carrier family 9A1) is an isoform of sodium–hydrogen antiporter that in humans is encoded by the SLC9A1 gene.The Na+/H+ antiporter (SLC9A1) is a ubiquitous membrane-bound enzyme involved in volume- and pH-regulation of vertebrate cells. It is inhibited by the non-specific diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, tumor promoters, and others.Sodium–hydrogen antiporter 1 has been shown to interact with carbonic anhydrase II and CHP. It is also the target of the experimental drug rimeporide, which is being developed for the treatment of Duchenne muscular dystrophy.
CAS Number
9007-83-4
Product Name Alternative
amiloride-sensitive antibody APNH antibody APNH1 antibody FLJ42224 antibody Na Li countertransporter antibody Na (+)/H (+) antiporter antibody Na (+)/H (+) exchanger 1 antibody Na+ H+ antiporter amiloride-sensitive antibody Na+ H+ antiporter antibody Na+ H+ exchanger 1 antibody NHE-1 antibody NHE1 antibody OTTHUMP00000004468 antibody SL9A1_HUMAN antibody SLC9A1 antibody Sodium / Hydrogen Exchanger 1 antibody Sodium hydrogen exchanger 1 antibody Sodium/hydrogen exchanger 1 antibody solute carrier family 9 antibody Solute carrier family 9 member 1 antibody Solute carrier family 9 sodium hydrogen exchanger isoform 1 antiporter Na+ H+ amiloride sensitive antibody Solute carrier family 9 subfamily A (NHE1 cation proton antiporter 1) member 1 antibody Solute carrier family 9 subfamily A member 1 antibody
Abbreviation
Sodium/hydrogen exchanger 1,Na (+)/H (+) exchanger 1 Solute carrier family 9 member 1,NHE-1
Swiss Prot
P19634 Human, Q61165 Mouse, P26431 Rat
Cellular Locus
Cell membrane, Endoplasmic reticulum, Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within mouse NHE-1 aa 36-85 / 820.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
Rat skin lysates, A431, 293T, LOVO, human kidney tissue, mouse colon tissue, human small intestine tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1000;IHC-P: 1:50-1:200;IF-Cell: 1:50-1:200;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 91/61 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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