GL-331

• UNSPSC Description:

  GL-331 is a potent anti-cancer agent. GL-331 has demonstrated more efficacious anti-cancer activity in both the in vitro and in vivo lymphoma systems[1].

• Target Antigen:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/gl-331.html

• Smiles:

  O=C1OC[C@]2([H])[C@H](NC3=CC=C([N+]([O-])=O)C=C3)C4=C(C=C5OCOC5=C4)[C@@H](C6=CC(OC)=C(O)C(OC)=C6)[C@]21[H]

• Molecular Weight:

  520.49

• References & Citations:

  [1]You Y. Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents. Curr Pharm Des. 2005;11(13):1695-717. |[2]Huang TS, et al. A novel podophyllotoxin-derived compound GL331 is more potent than its congener VP-16 in killing refractory cancer cells. Pharm Res. 1999 Jul;16(7):997-1002.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  127882-73-9