YGZ-331

• Description:

  YGZ-331 is a sedative with a calming effect. YGZ-331 is a derivative of the adenosine nucleoside NGBA, which can increase GABA levels. YGZ-331 exerts a sedative-hypnotic effect by activating A1R and A2aR, and inhibiting CaMKII phosphorylation (pCaMKII) levels. YGZ-331 can reduce the spontaneous motor activity of mice[1].

• UNSPSC:

  12352005

• Target:

  Adenosine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ygz-331.html

• Smiles:

  OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N[C@H](C4=CC=CC=C4)CC)O1

• Molecular Formula:

  C19H23N5O4

• Molecular Weight:

  385.42

• References & Citations:

  [1]Tang B, et al. The mechanism study of YZG-331 on sedative and hypnotic effects[J]. Behavioural Brain Research, 2022, 428: 113885.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1350113-04-0]