Products for Research Use Only
RegisterLogin

GL-1196

CAT: 0804-HY-124398Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-124398Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GL-1196 is an inhibitor of PAK4. GL-1196 can suppress the proliferation and invasion of gastric cancer cells. GL-1196 inhibits PAK4-mediated signaling pathways. GL-1196 can hinder the proliferation of human gastric cancer cells through suppressing PAK4/c-Src/EGFR/CyclinD1 and CDK4/6. GL-1196 can reduce filamentous pseudopodia formation and induce filamentous pseudopodia formation and promote cell elongation in SGC7901 and BGC823 cells. GL-1196 can be studied in anti-cancer research[1][2].
CAS Number
591242-70-5
UNSPSC
12352005
Target
PAK
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=S1(N=C(N(CC2=C(O)C=CC=C2)C3=CC=C(C=C3)Cl)C4=C1C=CC=C4)=O
Molecular Formula
C20H15ClN2O3S
Molecular Weight
398.86
References & Citations
[1]Huang, G., et al., (2025) . P21-activated kinase 4: a potent oncogene, molecular mechanisms and opportunities for targeted therapy. Cancer cell international, 25 (1), 409.|[2]Zhang, J., et al., (2024) . Correction: Zhang et al. GL-1196 Suppresses the Proliferation and Invasion of Gastric Cancer Cells via Targeting PAK4 and Inhibiting PAK4-Mediated Signaling Pathways. Int. J. Mol. Sci. 2016, 17, 470. International journal of molecular sciences, 25 (24), 13456.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-126876GL-V9
HY-W440556GL-522
HY-19188GL-331
HY-P990260-01Anti-Mouse CD86/B7-2 Antibody (GL-1)
HY-155378PZ-1190
HY-124543-01MRS-1191
HY-16196-01ENMD-1198
HY-120882-01BM-1197
HY-124543R-01MRS-1191 (Standard)
HY-P991066-01ARGX-119

Alternative Products

CatalogName
MPM00037mmu-miR-1196 Primers
mm0034AdmiRa-mmu-mir-1196 Virus
MNM01076mmu-miR-1196 miRNA Antagomir
MBS1244776-01Recombinant Tityus stigmurus Peptide 1196
MIM01076mmu-miR-1196 miRNA Inhibitor
CRB1001781-01SARS-CoV-2 Spike (1196-1205)
mm5054AdmiRa-mmu-miR-1196-Off Virus
mm30054LentimiRa-Off-mmu-miR-1196 Vector
EMk27608Monkey GLα (GLα) ELISA Kit
CSB-PA515269LA01HWW-01GL Antibody

Popular Products