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AVLX-125

CAT: 0804-HY-P10212Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10212Size:1 Each
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Description
AVLX-125 (UCCB01-125) is a PSD-95 and PDZ domain inhibitor with Kd value of 10 nM. AVLX-125 can be used in the study of inflammatory pain[1][2].
CAS Number
1786434-31-8
Product Name Alternative
UCCB01-125
UNSPSC
12352209
Target
IGluR
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/avlx-125.html
Solubility
10 mM in DMSO
Smiles
CC(C)[C@@H](C(O)=O)NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC(CCOCCOCCOCCOCCOCCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C62H104N10O29
Molecular Weight
1453.54
References & Citations
[1]Haugaard-Kedström L M, et al. Targeting PSD-95 as a novel approach in the treatment of stroke. Neuroprotective Therapy for Stroke and Ischemic Disease, 2017: 157-184.|[2]Andreasen JT, et al. UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: comparison with the NMDA receptor antagonist MK-801. Neuropharmacology. 2013 Apr;67:193-200.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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