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NBD-125

CAT: 0804-HY-133739Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-133739Size:1 Each
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Description
NBD-125 (B-12), a berberine analogue, is an RXRα activator, with an IC50 of 31.10 μM in KM12C cell[1].
CAS Number
2367641-24-3
UNSPSC
12352005
Target
RAR/RXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nbd-125.html
Solubility
10 mM in DMSO
Smiles
COC1=C2C=[N+](CCC3=C4C=CC(OC)=C3)C4=CC2=CC=C1.[Cl-]
Molecular Formula
C19H18ClNO2
Molecular Weight
327.80
References & Citations
[1]Beibei Xu, et al. Structure-Activity Relationship Study Enables the Discovery of a Novel Berberine Analogue as the RXRα Activator to Inhibit Colon Cancer. J Med Chem. 2020 Jun 11;63 (11) :5841-5855.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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