TH-Z145

CAT: 0804-HY-150168-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-150168-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

TH-Z145, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 210 nM) [1].

CAS Number

2260887-57-6

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/th-z145.html

Concentration

10mM

Purity

99.69

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=P(O)(C(P(O)(O)=O)CC1=CC(OCCCCCCCC)=CC=C1)O

Molecular Formula

C16H28O7P2

Molecular Weight

394.34

References & Citations

[1]Xia Y, et al. The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery. Cell. 2018 Nov 1;175 (4) :1059-1073.e21.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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