DEALA-Hyp-YIPD

CAT: 0804-HY-P5908Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-P5908Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

DEALA-Hyp-YIPD is an HIF-1α peptide that inhibits VHL/HIF-1α interaction with an IC50 of 0.91 μM and a Kd of 180 nM[1].

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/deala-hyp-yipd.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N1[C@@H](C[C@@H](O)C1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H]([C@@H](C)CC)C(N3[C@@H](CCC3)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N

Molecular Formula

C50H74N10O19

Molecular Weight

1119.18

References & Citations

[1]Buckley DL, et al. Targeting the von Hippel-Lindau E3 ubiquitin ligase using small molecules to disrupt the VHL/HIF-1α interaction. J Am Chem Soc. 2012 Mar 14;134 (10) :4465-8.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

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HY-P5915	FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2
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HY-P2788	Hyp-Phe-Phe
HY-W008205-01	Fmoc-Hyp-OH
HY-I0781-01	Boc-Hyp-OH
HY-65039-01	Boc-Hyp-OMe
HY-W008370-01	Z-Hyp-OMe
HY-P4550-01	H-Hyp-Gly-OH
HY-P5338-01	H-Ala-Hyp-OH

Alternative Products

Catalog	Name
T82595-01	DEALA-Hyp-YIPD
7287/1	FAM-DEALA-Hyp-YIPD
TP3456-01	FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2
M40508	Gly-Hyp\|H-Gly-Hyp-OH
MBS5781707	HyP-1
T206198-01	Hyp-dBET1
YP-W17121-01	Human Pro-Hyp (Pro-Hyp) ELISA Kit
BA9454-100000	Boc-Hyp-OEt
A-4535.0005	Boc-Hyp-OBzl
4025531.0005	Fmoc-Hyp-OH

DEALA-Hyp-YIPD

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