Boc-Hyp-OMe

CAT: 0804-HY-65039-01Size: 250 gDry Ice: NoHazardous: No
CAT#:0804-HY-65039-01Size:250 g
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Boc-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].
CAS Number
[74844-91-0]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/boc-hyp-ome.html
Purity
99.94
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@H](C(OC)=O)C[C@@H](O)C1)OC(C)(C)C
Molecular Formula
C11H19NO5
Molecular Weight
245.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16 (5) :315-337.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-985.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker

Related Products

CatalogName
HY-W008370-01Z-Hyp-OMe
HY-76043-01H-Hyp-OMe (hydrochloride)
HY-W052529-01Boc-Hyp-OEt
HY-42364-01Boc-Glu (OMe) -OMe
HY-I0781-01Boc-Hyp-OH
HY-W016429-01H-cis-Hyp-OMe (hydrochloride)
HY-W041862-01Boc-Gly-OMe
HY-40118-01Boc-Pro-OMe
HY-23122-01Boc-His-OMe
HY-W002173-01Boc-Ala-OMe

Alternative Products

CatalogName
5-04904Boc-Hyp-OMe
A-3115.0005Boc-cis-Hyp-OMe
OR1001126-01Rel-Boc-Hyp-OMe
5-04948Boc-D-trans-Hyp-OMe
5-04933Z-Hyp-OMe
5-04936Z-Hyp(tBu)-OMe
F-1660.0100H-Hyp-OMe · HCl
5-04890H-Hyp-OMe·HCl
443249-01Boc-hyp-obzl
A-4405.0005Boc-Hyp-OtBu

Popular Products