Hyp-dBET1

CAT: 0931-MF-0114270-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0114270-01Size:10 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Target
Epigenetic Reader Domain|||PROTACs
Related Pathways
PROTAC|||Chromatin/Epigenetic
Bioactivity
Hyp-dBET1 is a PROTAC degrader targeting BRD4, with an IC50 value of 3.4 ?M in MDA-MB-231 cells. Under hypoxic conditions, Hyp-dBET1 becomes active, recruiting E3 ubiquitin ligase, and facilitates the degradation of BRD4 via the ubiquitin-proteasome system. Hyp-dBET1 is applicable in anti-cancer research.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Popular Products