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Hyp-dBET1

CAT:
931-T206198-01
Size:
10 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Hyp-dBET1 - image 1

Hyp-dBET1

  • Target :

    Epigenetic Reader Domain|||PROTACs

  • Related Pathways :

    PROTAC|||Chromatin/Epigenetic

  • Bioactivity :

    Hyp-dBET1 is a PROTAC degrader targeting BRD4, with an IC50 value of 3.4 ?M in MDA-MB-231 cells. Under hypoxic conditions, Hyp-dBET1 becomes active, recruiting E3 ubiquitin ligase, and facilitates the degradation of BRD4 via the ubiquitin-proteasome system. Hyp-dBET1 is applicable in anti-cancer research.

  • Shipping Conditions :

    Cool pack

  • Storage Temperature :

    -20°C

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