CTP Synthetase-IN-1

CAT:

804-HY-152149-03

Size:

100 mg

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CAS Number: 2338811-71-3
UNSPSC Description: CTP Synthetase-IN-1 is a potent, orally active cytidine 5'-triphosphate synthetase (CTPS) inhibitor with IC50s of 32 nM and 18 nM for human CTPS1 and human CTPS2, respectively. CTP Synthetase-IN-1 has anti-inflammatory effects[1].
Target Antigen: DNA/RNA Synthesis
Type: Reference compound
Related Pathways: Cell Cycle/DNA Damage
Applications: COVID-19-anti-virus
Field of Research: Inflammation/Immunology
Assay Protocol: https://www.medchemexpress.com/ctp-synthetase-in-1.html
Solubility: DMSO : 100 mg/mL (ultrasonic)
Smiles: O=C(C(C)(C)C1=CSC(NS(=O)(C2CC2)=O)=N1)NC3=NC=C(C4=NC(C(F)(F)F)=CN=C4)C=C3
Molecular Weight: 512.53
References & Citations: [1]Andrew Novak, et al. Discovery and Optimization of Potent and Orally Available CTP Synthetase Inhibitors for Use in Treatment of Diseases Driven by Aberrant Immune Cell Proliferation. J Med Chem. 2022 Dec 22;65(24):16640-16650.
Shipping Conditions: Room Temperature
Clinical Information: No Development Reported

Cat	Name
HY-152149-04	CTP Synthetase-IN-1
HY-152149-03	CTP Synthetase-IN-1
HY-152149-02	CTP Synthetase-IN-1
HY-152149-01	CTP Synthetase-IN-1
HY-151148	Trypanothione synthetase-IN-1
HY-152149-06	CTP Synthetase-IN-1
HY-152149-05	CTP Synthetase-IN-1
HY-108939-01	Aminoacyl tRNA synthetase-IN-1
HY-108939-03	Aminoacyl tRNA synthetase-IN-1
HY-108939-02	Aminoacyl tRNA synthetase-IN-1

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