STF-62247

• Description :

  STF-62247 is an autophagy inducer that selectively cytotoxic to VHL-deficient renal cell carcinoma (IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively) [1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H319

• Target :

  Autophagy

• Type :

  Reference compound

• Related Pathways :

  Autophagy

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/STF-62247.html

• Purity :

  98.69

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  CC1=CC(NC2=NC(C3=CC=NC=C3)=CS2)=CC=C1

• Molecular Formula :

  C15H13N3S

• Molecular Weight :

  267.35

• Precautions :

  H302, H319

• References & Citations :

  [1]Turcotte, S. et al. A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. Cancer cell 14, 90-102, doi:10.1016/j.ccr.2008.06.004 (2008)

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [315702-99-9]