STF-62247

• Description:

  STF-62247 is an autophagy inducer that selectively cytotoxic to VHL-deficient renal cell carcinoma (IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively) [1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H319

• Target:

  Autophagy

• Type:

  Reference compound

• Related Pathways:

  Autophagy

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/STF-62247.html

• Purity:

  98.69

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  CC1=CC (NC2=NC (C3=CC=NC=C3) =CS2) =CC=C1

• Molecular Formula:

  C15H13N3S

• Molecular Weight:

  267.35

• Precautions:

  H302, H319

• References & Citations:

  [1]Turcotte, S. et al. A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. Cancer cell 14, 90-102, doi:10.1016/j.ccr.2008.06.004 (2008)

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  315702-99-9