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PD 140376

CAT: 0804-HY-120302Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120302Size:1 Each
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Description
PD 140376 is a potent antagonist for the cholecystokininB/gastrin receptor, with Ki values of 0.18 nM and 0.21 nM in guinea-pig cortex and gastric gland membranes, respectively[1].
CAS Number
149027-97-4
UNSPSC
12352005
Target
Cholecystokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pd-140376.html
Smiles
O=C(C[C@H](CC1=CC=C(C=C1)N)NC([C@@](C)(CC2=CNC3=C2C=CC=C3)NC(OC4C5CC(CC4C6)CC6C5)=O)=O)O
Molecular Formula
C33H40N4O5
Molecular Weight
572.69
References & Citations
[1]J C Hunter, et al. [3H]PD 140376: a novel and highly selective antagonist radioligand for the cholecystokininB/gastrin receptor in guinea pig cerebral cortex and gastric mucosa. Mol Pharmacol. 1993 Apr;43 (4) :595-602
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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