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IIQLPEIVVV (TFA)

CAT: 0804-HY-P6374Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P6374Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IIQLPEIVVV TFA is a specific inhibitor of Drp1-Mff interaction. IIQLPEIVVV TFA can distinguish physiological from pathological fission and block physiological fission, thus leading to mitochondrial dysfunction. IIQLPEIVVV TFA can be used in the study of Huntington's disease[1].
UNSPSC
12352209
Target
Dynamin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/iiqlpeivvv-tfa.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)N.OC(C(F)(F)F)=O.[x]
Molecular Formula
C54H95N11O14.xC2HF3O2
Molecular Weight
1122.40 (free base)
References & Citations
[1]Kornfeld O S, et al. Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo[J]. Scientific reports, 2018, 8 (1) : 14034.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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