Rf470 (TFA)

• Description :

  Rf470 (Rotor NO.4) TFA is a FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently incorporated into peptidoglycan by bacteria. Rf470 TFA has extremely weak fluorescence in the free state, but its fluorescence is significantly enhanced when it is catalytically incorporated into peptidoglycan by transpeptidases. Through fluorescence changes, Rf470 TFA can be used for real-time monitoring of peptidoglycan biosynthesis, detection of transpeptidase activity, and screening of antibiotics, etc[1].

• Product Name Alternative :

  Rotor NO.4 (TFA)

• UNSPSC :

  12352211

• Target :

  Bacterial; Fluorescent Dye

• Related Pathways :

  Anti-infection; Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Purity :

  95.55

• Smiles :

  OC(C(F)(F)F)=O.OC([C@H](N)CCCCNC(CCN1C2=CC=C(C3=CC=C(/C=C(C#N)/C(O)=O)S3)C=C2CCC1)=O)=O

• Molecular Formula :

  C28H31F3N4O7S

• Molecular Weight :

  624.63

• References & Citations :

  [1]Michael VanNIEUWENHZE, et al. Molecular rotor-based d-amino acids as tools for imaging peptidoglycan biosynthesis. WO2019157233A1. 2019-08-15.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2369899-34-1]