USP7-IN-8

• UNSPSC Description:

  USP7-IN-8 (example 81) is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM in an Ub-Rho110 assay. USP7-IN-8 shows no activity against USP47 and USP5. USP7-IN-8 has anticancer effects[1].

• Target Antigen:

  Deubiquitinase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/usp7-in-8.html

• Smiles:

  O=C(NC)C1=CC=C(C2=C(CC)C(C3=CC=C(O)C=C3)=C(N)N=C2)C=C1

• Molecular Weight:

  347.41

• References & Citations:

  [1]Robert Blake, et al. Usp7 inhibitor compounds and methods of use. US20160272588A1.

• Shipping Conditions:

  Blue Ice

• CAS Number:

  2009273-60-1