USP7-IN-8

CAT: 804-HY-134817-01Size: 5 mgDry Ice: NoHazardous: No
5 mgSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
USP7-IN-8 (example 81) is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM in an Ub-Rho110 assay. USP7-IN-8 shows no activity against USP47 and USP5. USP7-IN-8 has anticancer effects[1].
CAS Number
[2009273-60-1]
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp7-in-8.html
Purity
99.04
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
O=C(NC)C1=CC=C(C2=C(CC)C(C3=CC=C(O)C=C3)=C(N)N=C2)C=C1
Molecular Formula
C21H21N3O2
Molecular Weight
347.41
References & Citations
[1]Robert Blake, et al. Usp7 inhibitor compounds and methods of use. US20160272588A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported