EVT-401

• Description :

  EVT-401 (P2X7 receptor antagonist-1) is a purinergic P2X7 receptor antagonist. EVT-401 has efficacy of combating neuroinflammation[1].

• UNSPSC :

  12352005

• Target :

  P2X Receptor

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/evt-401.html

• Purity :

  99.89

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(NC1=C(C)C=CC2=C1C=CN(C(C)CO)C2=O)CC3=CC=C(C(F)(F)F)C(F)=C3

• Molecular Formula :

  C22H20F4N2O3

• Molecular Weight :

  436.40

• References & Citations :

  [1]Binan Zhu, et al. Identification and characterization of related substances in EVT-401 by hyphenated LC-MS techniques. J Pharm Anal

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  P2X7 Receptor