BSI-401

• Description :

  BSI-401 is an orally active PARP-1 inhibitor. BSI-401 alone and in synergism with Oxaliplatin (HY-17371) inhibits pancreatic cancer[1].

• UNSPSC :

  12352005

• Target :

  PARP

• Related Pathways :

  Cell Cycle/DNA Damage; Epigenetics

• Field of Research :

  Cancer

• Smiles :

  O=C1C=CC2=C(I)C([N+]([O-])=O)=CC=C2O1

• Molecular Formula :

  C9H4INO4

• Molecular Weight :

  317.04

• References & Citations :

  [1]Melisi D, et al. Oral poly (ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity. Clin Cancer Res. 2009 Oct 15;15 (20) :6367-77.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PARP1

• CAS Number :

  [142404-10-2]