CBu-Cit-OH

CAT: 0804-HY-111121Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-111121Size:1 Each
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Description
CBu-Cit-OH (Mal-cyclobutane-1) is an ADC Linker that can be used to synthesize ADCs[1].
CAS Number
[1799663-03-8]
Product Name Alternative
Mal-cyclobutane-1,1-dicarboxamide-Cit-PAB
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cbu-cit-oh.html
Solubility
10 mM in DMSO
Smiles
OCC1=CC=C(NC([C@H](CCCNC(N)=O)NC(C2(C(NCCCCCN3C(C=CC3=O)=O)=O)CCC2)=O)=O)C=C1
Molecular Formula
C28H38N6O7
Molecular Weight
570.64
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Wei B, et al. Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity. J Med Chem. 2018 Feb 8;61 (3) :989-1000.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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