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Fmoc-Cit-OH

CAT: 0804-HY-W008064-01Size: 25 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W008064-01Size:25 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fmoc-Cit-OH (Fmoc-L-Citrulline) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a degradable ADC linker composed of a valine-citrulline (Val-Cit) motif[1].
CAS Number
133174-15-9
Product Name Alternative
Fmoc-L-Citrulline
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Amino Acid Derivatives
Type
Peptides
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-cit-oh.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC(NCCC[C@@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O
Molecular Formula
C21H23N3O5
Molecular Weight
397.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Pryyma, et al. "Rapid, high-yielding solid-phase synthesis of cathepsin-B cleavable linkers for targeted cancer therapeutics." Bioconjugate Chemistry 31.12 (2020) : 2685-2690.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Peptides
Clinical Information
No Development Reported

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