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PF-06795071

CAT: 0804-HY-111512-01Size: 5 mgDry Ice: NoHazardous: No
CAT#: HY-111512-01Size: 5 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-06795071 is a potent and selective covalent MAGL inhibitor with an IC50 of 3 nM[1].
CAS Number
[2075629-81-9]
UNSPSC
12352005
Target
MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/PF-06795071.html
Purity
99.31
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC[C@H](C(F)(F)F)OC(N1C[C@]([C@@]2([H])C1)([H])[C@H]2C3=NN(C4=CC=C(F)C=C4)C=C3)=O
Molecular Formula
C18H17F4N3O3
Molecular Weight
399.34
References & Citations
[1]McAllister LA, et al. Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. J Med Chem. 2018 Apr 12;61 (7) :3008-3026.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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